Coarse-grained models of Intrinsically disordered proteins - Physics

There is a growing interest to study Intrinsically disordered proteins (IDPs). These proteins do not form unique three-dimensional structures. On the contrary the disordered structure and the associated noise can trigger a variety of tasks, often complementing their ordered counterparts. The IDP complexes has also been realized to play a central to the pathology of several degenerative diseases: α-synuclein (Parkinson’s disease), tau (Alzheimer’s disease), and IAPP (Type II Diabetes). We use mesoscale models of IDPs, particularly those have been associated with diseases and study their conformations and dynamics using a variety of computer simulation methods. Students will be running simulation, analyze and visualize data using the code that will be provided. Some knowledge of Python will be a plus, although not necessary. They will be encouraged to present the research results during the showcase of undergraduate research and at the APS meetings.

Project Dates

Start Date: 10/2/2023 - End Date: 5/31/2024

Students Needed

Type of Project


Student Responsibilities

Students need to learn how to use a few well established simulation platforms, participate in weekly meetings and work with a long term goal to present their results at UCF and other national and international meetings

Time Commitment

4-5 hours per week hour(s)

Student Requirements

should register for a zero-credit research.

Interested in Working With the Following Programs

For EXCEL URE Students Only
Honors Undergraduate Thesis
Independent Research Credit (4912)
McNair Scholars
Research and Mentoring Program
Summer Undergraduate Research Fellowship

Additional Notes

Student with excellent credentials should seek various undergraduate research funding opportunities through EXCEL, COMPASS etc. at UCF .

Position Overview

  • Date Posted: 10-06-2023
  • Location:
    • Orlando (Main Campus)
  • Paid: Yes